PL2543

USB2.0 to Quad UART Bridge Controller

OVERVIEW

The PL2543 is a high performance USB2.0 to Quad UART bridge controller of PL2303 series family. The PL2543 provides 4 channels UART solution supporting RS232 / 422 / 485 serial device to any USB host. The USB interface is fully compliant to the USB2.0 (High-Speed) specification. It supports not only in-box CDC(Communication Device Class) driver, also Prolific proprietary robust driver of Windows / Mac / Linux OSes that could simulate the traditional COM port on most operating systems allowing the existing applications based on COM port to easily migrate and be made USB ready.

The PL2543 equips an internal oscillator and does not require an external crystal/oscillator. It supports UART baud rate from 1bps to 24Mbps. By taking advantage of USB bulk transfer mode and large data buffers, PL2543 is capable of achieving higher throughput compared to traditional UART (Universal Asynchronous Receiver Transmitter) ports.

FEATURE

  • USB2.0 (High-Speed) Specification compliant
  • USB-IF certified TID 6180
  • Royalty-free USB to Virtual COM Port drivers for Windows, Mac, Linux, and Android
  • Support CDC / V-COM USB class
  • Support Battery Charger (BC1.2) detection
  • On-chip 5v to 3.3v / 1.2v regulator
  • Individual IN / OUT FIFO buffer per port
  • Programmable baud rate from 1bps to 24Mbps
  • 4 channels UART operation simultaneously
  • Support RS232 / RS422 / RS485
  • Hardware / Software flow control
  • Adjustable high / low watermark level
  • On-chip MTP for USB device, configuration, and serial number descriptors customization
  • 11 GPIOs for custom applications
  • Support PWM and access LED
  • -40℃ to 85℃ operating temperature

PACKAGE

  • QFN64

Product Brochure

說明版本更新日期
下載PL2543 product brochure20250417

Datasheets & Notice

說明版本更新日期
下載PL2543 USB 2.0 to 4-port Full UART Controller DatasheetV1.02025/05/02

Drivers & Software

說明版本更新日期
下載Windows Driver Installer Setup Program ( Win7 / Win8.1 / Win10 / Win11)
Installer version & Build date: v3.3.0.0 (2025-06–17)

Windows 11 ( 64-bit ) WDF WHQL Driver: v7.1.5.0 (05/20/2025) / v4.1.6.0 (04/16/2025)

(For PL2543 / PL2523 / PL2565 / PL2503 versions)
– Windows 11 Certified WHQL Driver ( 24H2 versions)
– Auto-download driver via Windows Update (Windows 11)

Windows 7/8.1/10 (32 & 64-bit) WDF WHQL Driver: v7.0.5.0 (06/19/2025) / v4.0.6.0 (03/20/2025)

(For PL2543 / PL2523 / PL2565 / PL2503 versions)
– Windows 10 Certified WHQL Driver (TH1 1507, TH2 1511, RS1 1607, RS2 1703, RS3 1709, RS4 1803,RS5 1809,19H1 1903, 19H2 1909, 20H1 VB, 21H1,versions)
– Windows 7, 8.1 Certified WHQL Driver
– Compatible with Windows Server 2008, 2008R2, 2012, 2012R2, 2016, 2019 , 2022
– Auto-download driver via Windows Update (Windows 7, 8.1, 10)

– Installer Language Support: English (default),

– For Prolific USB VID_067B&PID_2343, PID_2565,PID_2503
– Includes Certification Report, Driver Release Notes
– Installer supports silent install (add “/s” parameter when running program)

v3.3.0.02025/06/17
下載Mac OS X Universal Binary Driver v1.2.3 (PKG file format)

For Mac OS Ventura (version 13)
For Mac OS Monterey (version 12.4)
For Mac OS Big Sur (version 11) –
For Mac OS Catalina (version 10.15) .
For Mac OS Mojave (version 10.14)
For Mac OS High Sierra (version 10.13)
For Mac OS X Sierra (version 10.12)
For Mac OS X El Capitan (version 10.11)
For Mac OS X Yosemite (version 10.10)
For Mac OS X Mavericks (version 10.9)

v1.2.32024/10/08
下載You can update CDC-ACM patch file to support hardware flow controlv1.0.02023/05/12
下載
PL2543 11-GPIO Mac OS Application Note
Includes GPIO Test Sample Program and Source Code
v1.0.02022/12/23
下載PL2543 11-GPIO LED Indicator Application Note
Includes GPIO Test Sample Program and Source Code
v1.0.0.32022/12/05

Reference Design Guide

說明版本更新日期
下載PL2543 Reference Design GuideV122024/10/14
下載PL2543 PCB Layout GuideV1.02021/12/21

Application Note & User Manual

說明版本更新日期
下載
下載

Test Reports

說明版本更新日期
下載
下載

MP Tools (For Vendors Only)

說明版本更新日期
下載
下載

Firmware (For Vendors Only)

說明版本更新日期
下載
下載

Prolific Internal Only

說明版本更新日期
下載
下載

Software

說明版本更新日期
下載
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